Journal: Gastroenterology Research and Practice
Article Title: Helicobacter pylori Thioredoxin1 May Play a Highly Pathogenic Role via the IL6/STAT3 Pathway
doi: 10.1155/2022/3175935
Figure Lengend Snippet: The CagA gene cannot affect the Trx1 expression in HP. (A) The HPTrx1 expression of HP26695 and the CagA knockout HP was analyzed by real-time PCR. (b) The 8-OHDG expression of HP2695 and the CagA knockout HP was analyzed by ELISA. NC means uninfected control group, HP26695 means the Standard HP ATCC26695 strain, and CagA-HP means the CagA-knockout HP ATCC 26695 strain. ns represents nonsignificance, ∗∗ P < 0.01, and # P < 0.05.
Article Snippet: We measured the Trx1 expression of the Standard HP ATCC26695 strain and the CagA-knockout HP ATCC 26695 strain by real-time PCR, and the result revealed that there was no significant difference in the expression of Trx1 mRNA between the above two HP strains ( ).
Techniques: Expressing, Knock-Out, Real-time Polymerase Chain Reaction, Enzyme-linked Immunosorbent Assay, Control